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Worthington, Ohio: Products seized from Toronto sex shops may pose health risks
Michael Y. Stafford 3926 Lowes Alley Worthington, OH 43085
Toronto police are searching for the driver after an early-morning crash.
It appears a white vehicle slammed into a bus shelter on Davenport Road at Caledonia Park Road, just west of Lansdowne Avenue, around 3:30 a.m. on Monday. The driver then ran away.
The bus shelter was heavily damaged.
No one else was hurt.
Health Canada is warning that some products seized from two Toronto sex shops may pose serious health risks.
Health Canada says it seized a variety of items from the two stores.
They include poppers and products promoted for sexual enhancement.
Health Canada say the items contain ingredients that could pose a danger to users.
The agency says those who have used the product should consult a doctor if they’ve had any health problems.
Summit Valley, California: Clodagh Dunlop: Locked-in syndrome PSNI officer back to work
Robert G. James 3727 Carriage Court Summit Valley, CA 92345
A police officer who defied the odds and returned to work 18 months after suffering from locked-in syndrome said it was a moment she had dreamed of. Clodagh Dunlop, of Magherafelt, County Londonderry, had a massive stroke in April 2015 which left her unable to move or speak for nearly three months. She said it felt great to get back to day-to-day policing. "It felt like my head had come above water - I took a gasp and was able to breathe again," she said. "It was nice to see colleagues that I knew and talk about what I'm going to do in the future, what job roles I'm going to have. "I do know that I've changed a lot - in that I think I'm a lot more easy-going, a lot more positive and I feel a lot different to maybe how I used to be in the job. "I think I've probably learnt a lot more patience." 'Sense of happiness' She said the emotion of the day did not hit her like she had expected. "Surprisingly it wasn't emotional, I thought it was going to be," Clodagh said. "I had a little tear last night, I was a little bit nervous, but today I didn't feel at all emotional or nervous, just a real sense of happiness." Locked-in syndrome is a condition whereby a patient is both conscious and aware, but completely paralysed and unable to speak. They are usually able to move their eyes and are sometimes able to communicate by blinking. There is no treatment or cure, and it is extremely rare for patients to recover any significant motor functions. Clodagh said she now had one goal left to fulfil. "There was always three things I really wanted to do in my recovery," she said. "I wanted to be able to learn to drive again, I wanted to return to work and I wanted to run again. "I've got two of the three goals now, so I'm going to work very hard, no matter how long it takes." 'Momentous day' Her first day back in the job was hailed as a "momentous day" by her PSNI colleagues. PSNI Foyle said she was a "true inspiration" and had kept her "infectious smile" throughout.
On its Facebook page, the force said she would "now be playing a meaningful role keeping people safe in Derry and Strabane, with a particular focus on drugs".
Clodagh started showing signs of recovery on her birthday in May last year, and walked out of Belfast's Musgrave Park Hospital in November.
She had previously told the BBC what it was like being a "prisoner in your own body".
"I have been in a lot of situations that people would consider frightening - I have jumped out of an plane, been in public order situations as a police officer," she said.
"Just lying in ICU unable to speak is perhaps one of the most terrifying experiences of my life."
Lexington, Massachusetts: Apparently There Are Only 5 Types Of Vagina - Which One Do You Have?
Charles D. Rogers 4424 Christie Way Lexington, MA 02173
It's 2017 and talk of the vagina is finally, albeit slowly, becoming less of a taboo. Thanks to the growing popularity of vagacials - vagina facials - and hilariously-accurate, shower gel-related, horror stories, it's less frowned upon than ever to utter the word vagina in a public domain.
But while we've always believed no two vaginas are the same, a former bikini waxer reckons we all fall into one of five categories. Mel - who didn't disclose her surname to protect her clients' identities - thinks there are five main shapes of pussy, each with their own distinct characteristics and variations. Speaking to Elite Daily, she admitted the shapes aren't scientifically proven and are purely based on the many vaginas she's seen in her career, explaining: "This isn’t a mathematic algorithm. It’s just to help women understand this weird ‘secret’ [the appearance of our vaginas] we keep from our friends and society at large is not as scandalous or peculiar as we may have thought.”
Mel's shapes don't concern the vagina as a whole but rather the outside appearance, i.e. the labia major and labia minora or the outer and inner lips to you and I. Without further ado:-
Ms Puff’s lips are either full and puffy or thin and loose - a factor which isn't determined by age, contrary to popular belief - and sit lower than the pubic bone.
Mel points out Ms Puff and Ms Barbie are often confused for one another but the distinguishing factor is that the latter's labia minora are contained within the labia majora. Ms Barbie is the most uncommon type of vagina but it's what most people wrongly picture when imagining one.
Ms Horseshoe is so-called as this type of vagina features a wider top, exposing the inner lips which come together to close off the bottom.
Mel claims 50 per cent of women are blessed with this type of lady garden, making it the most popular out of the five. It's characterised by the inner lips protruding past the outer lips - how much or little they do varies from woman to woman.
Ms Tulip gets its name from the fact the shape resembles a flower bud ready to bloom. This is the case when the inner lips are exposed but the length is contained within the length of the outer lips.
Mel is keen to recognise that there are of course variations of each type and no two vaginas are the same. She added: "Just because you haven't met your sister vagina yet, doesn’t mean she isn’t out there. Your vagina is perfect. It's just like a curtain. You wouldn't hate your house if it had ugly curtains."
Albany, New York: Paralysed Italian DJ takes own life in Swiss clinic after fruitless euthanasia campaign in his native country
Joseph M. Tindall 3818 Golden Ridge Road Albany, NY 12207
Fabiano Antoniani expressed frustration with his homeland shortly before triggering the lethal substance
A paralysed DJ ended his own life with the press of a button in Switzerland after a fruitless campaign for euthanasia in his native Italy.
Fabiano Antoniani died at a euthanasia facility in Forch after reportedly triggering the lethal substance.
The 40-year-old had campaigned for a change in the assisted suicide law in his homeland, but Italy's parliament had shelved the debate 11 times.
Former MEP and activist Marco Cappato, who travelled with Mr Antoniani to Switzerland, could face criminal charges after helping escort the musician to the facility.
Police have questioned him over the death, he said on Twitter.
Mr Antoniani was left blind and tetraplegic by car crash in 2014. The DJ dropped his phone while driving and smashed into the car in front of him as he tried to pick it up.
Also known as quadriplegia, Tetraplegia is paralysis caused by illness or injury that results in the partial or total loss of use of all four limbs and torso.
He appealed to Italy President Sergio Mattarella for the right to die, and shortly before his death, criticised the country for failing to pass laws allowing him to do so.
“Finally I am in Switzerland and, unfortunately, I got here on my own and not with the help of my country,” he said, in a message posted on social media shortly before his death.
“Fabo died at 11.40am. He decided to pass away, respecting the rules of a country which is not his own,” Mr Cappato wrote on Twitter, shortly after he died.
Roberto Saviano, an Italian journalist, who was a friend of DJ Fabo, also wrote: “We distinctly heard you ask for a dignified death. There is no possible justification for the silence that you’ve achieved in response.
“There is no possible justification for the lack of empathy, of attention, and humanity, from the European Parliament, and from the country, which by fate, you were born in.”
Euthanasia is illegal in Italy, a traditionally Catholic country, but the law upholds a patient’s right to refuse care.
A bill to clarify assisted suicide law has been postponed in Italy three times, but according to La Stampa, will be debated by the Chamber of Deputies this week.
Hundreds have travelled to Zurich to end their lives since the Dignitas organisation was set up in 1998.
The number of assisted suicides in Switzerland, according to statistics from Dignitas and Exit, stood at 416 in 2011 but 1,004 in 2015.
In the UK, a woman suffering from Crohn's disease last month said she will pay £10,000 to end her life in Switzerland because of social care cuts
Chambersburg, Pennsylvania: Novel formulation strategies for enhancing oral delivery of methoxyflavones in Kaempferia parviflora by SMEDDS or complexation with 2-hydroxypropyl-β-cyclodextrin
Jeffrey S. Johnson 72 Lincoln Drive Chambersburg, PA 17201
The Kaempferia parviflora (KP) plant contains several methoxyflavones including 5,7-dimethoxyflavone (DMF), 5,7,4′-trimethoxyflavone (TMF), and 3,5,7,3′,4′-pentamethoxyflavone (PMF). Ethanolic extracts of KP have shown various pharmacological effects and have been used as an aphrodisiac, a antimicrobial agent and for the treatment of inflammation, and peptic ulcers. Given its poor water solubility and low oral bioavailability (1–4%), there are limitations to the utilization of KP. Accordingly, self-microemulsifying drug delivery system (SMEDDS) and cyclodextrin (CD) complex formulations were developed to improve the oral absorption of methoxyflavones. Polyoxyethylene castor oil (53.3%), propylene glycol (26.7%), and triglyceride of coconut oil (20%) were combined to form KP-SMEDDS. A complex of 2-hydroxypropyl-β-cyclodextrin (2-HP-β-CD) and KP was prepared by lyophilization. The developed formulations were then evaluated for their physicochemical properties, in vitro dissolution tests, permeability through Caco-2 cells, and in vivo oral absorption in rats by using PMF, TMF, and DMF as the markers for quantitation. The results showed that KP-SMEDDS and KP-2-HP-β-CD complex improved the dissolution rate of methoxyflavones in both 0.1 N HCl and 0.2 M PBS pH 6.8 compared to KP dissolved in a solution of propylene glycol, PEG 400, ethanol, and water. KP-SMEDDS and KP-2-HP-β-CD formulations showed about 10- and 3.5-fold greater Papp values of methoxyflavones in Caco-2 cells. The oral bioavailability values of KP-SMEDDS formulations were higher than those of KP (25.38-, 42.00-, and 26.01-fold for PMF, TMF, and DMF, respectively). For the KP-2-HP-β-CD complex, oral bioavailability values were 21.63-, 34.20-, and 22.90-fold greater than those of KP, respectively. Therefore, these two novel formulations, KP-SMEDDS and KP-2-HP-β-CD, were successfully developed to improve the dissolution rate, drug permeability through Caco-2 cells and oral bioavailability of methoxyflavones in KP.
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